“Sceletium tortuosum is a succulent plant that is indigenous to South Africa and belongs to the family Mesembryanthemaceae. It has a long history of traditional use, and more recently, it has attracted attention for its possible utility in supporting and promoting a sense of well being in healthy people, and treating people with anxiety, stress or depression.”(Harvey, Alan L 1)
Kanna was used as early as the 17th century, used by two nomadic groups that scoured the lands of Karoo Namaqualand where Sceletium (Kanna) grew. The Khoi and the San.
“Kolben (1738) noted that the scarce root was ‘the greatest Chearer of the Spirits, and the noblest Restorative in the world’.” [sceletium.org]
Harvey, Alan L, et al. “Pharmacological Actions of the South African Medicinal and Functional
Food Plant Sceletium Tortuosum and Its Principal Alkaloids.” Journal of Ethnopharmacology, vol. 137, no. 3, 11 Oct. 2011, https://www.sciencedirect.com/science/article/abs/pii/S0378874111005113.
Smith, Michael T, et al. Journal of Ethnopharmacology, https://www.sceletium.org,13 July 1995.